Search on: SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION 
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Descriptor English:   Spectrometry, Mass, Electrospray Ionization 
Descriptor Spanish:   Espectrometría de Masa por Ionización de Electrospray 
Descriptor Portuguese:   Espectrometria de Massas por Ionização por Electrospray 
Synonyms English:   ESI Mass Spectrometry
Electrospray Ionization Mass Spectrometry
Mass Spectrometry, ESI
Spectrometry, ESI Mass  
Tree Number:   E05.196.566.600
Definition English:   A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry. 
History Note English:   2001 
Allowable Qualifiers English:  
CL classification EC economics
ES ethics HI history
IS instrumentation MT methods
ST standards SN statistics & numerical data
TD trends VE veterinary
Record Number:   35400 
Unique Identifier:   D021241 

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